loading...| Preferred Name |
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| Synonyms |
Cortisol cortisol 11beta,17,21-trihydroxypregn-4-ene-3,20-dione (11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione 4-pregnen-11beta,17alpha,21-triol-3,20-dione Reichstein's substance M Kendall's compound F hydrocortisone 11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione hydrocortisonum hidrocortisona 17-hydroxycorticosterone 11beta,17alpha,21-trihydroxy-4-pregnene-3,20-dione Hydrocortisone 11beta-hydrocortisone |
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| Definitions |
A 17alpha-hydroxy-C21-steroid that is pregn-4-ene substituted by oxo groups at positions 3 and 20 and hydroxy groups at positions 11, 17 and 21. Cortisol is a corticosteroid hormone or glucocorticoid produced by zona fasciculata of the adrenal cortex, which is a part of the adrenal gland. It is usually referred to as the "stress hormone" as it is involved in response to stress and anxiety, controlled by corticotropin-releasing hormone (CRH). It increases blood pressure and blood sugar, and reduces immune responses. |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_17650 |
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| charge |
0 |
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| database_cross_reference |
MeSH:D006854 SNOMEDCT:396458002 NCIt:C2290 LIPID_MAPS_instance:LMST02030001 DrugBank:DB00741 PMID:10438974 CAS:50-23-7 Beilstein:1354819 PDBeChem:HCY PMID:2268561 KEGG:C00735 LINCS:LSM-5980 Patent:US2602769 Drug_Central:1388 Wikipedia:Hydrocortisone KEGG:D00088 |
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| definition |
A 17alpha-hydroxy-C21-steroid that is pregn-4-ene substituted by oxo groups at positions 3 and 20 and hydroxy groups at positions 11, 17 and 21. Cortisol is a corticosteroid hormone or glucocorticoid produced by zona fasciculata of the adrenal cortex, which is a part of the adrenal gland. It is usually referred to as the "stress hormone" as it is involved in response to stress and anxiety, controlled by corticotropin-releasing hormone (CRH). It increases blood pressure and blood sugar, and reduces immune responses. |
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| formula |
C21H30O5 |
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| has_alternative_id |
CHEBI:24633 CHEBI:58221 CHEBI:3893 CHEBI:14023 |
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| has_exact_synonym |
Cortisol cortisol 11beta,17,21-trihydroxypregn-4-ene-3,20-dione |
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| has_obo_namespace |
chebi_ontology |
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| has_related_synonym |
(11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione 4-pregnen-11beta,17alpha,21-triol-3,20-dione Reichstein's substance M Kendall's compound F hydrocortisone 11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione hydrocortisonum hidrocortisona 17-hydroxycorticosterone 11beta,17alpha,21-trihydroxy-4-pregnene-3,20-dione Hydrocortisone 11beta-hydrocortisone |
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| has_role | ||
| id |
CHEBI:17650 |
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| in_subset | ||
| inchi |
InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1 |
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| inchikey |
JYGXADMDTFJGBT-VWUMJDOOSA-N |
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| label |
cortisol |
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| mass |
362.45990 |
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| monoisotopicmass |
362.20932 |
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| notation |
CHEBI:17650 |
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| smiles |
[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]1(C)[C@@]2([H])CC[C@]1(O)C(=O)CO |
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| subClassOf |