BioModels Ontology

Last uploaded: April 3, 2012
Preferred Name

felodipine

Definitions

The mixed (methyl, ethyl) diester of 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid. A calcium-channel blocker, it lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels. It is used in the management of hypertension and angina pectoris.

ID

http://purl.obolibrary.org/obo/CHEBI_585948

alternative term

FELODIPINE

InChIKey=RZTAMFZIAATZDJ-UHFFFAOYSA-N

(+-)-ethyl methyl 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate

3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate

felodipine

C18H19Cl2NO4

InChI=1S/C18H19Cl2NO4/c1-5-25-18(23)14-10(3)21-9(2)13(17(22)24-4)15(14)11-7-6-8-12(19)16(11)20/h6-8,15,21H,5H2,1-4H3

4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid ethyl methyl ester

ethyl methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

felodipinum

CCOC(=O)C1=C(C)NC(C)=C(C1c1cccc(Cl)c1Cl)C(=O)OC

felodipina

definition

The mixed (methyl, ethyl) diester of 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid. A calcium-channel blocker, it lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels. It is used in the management of hypertension and angina pectoris.

has role

http://purl.obolibrary.org/obo/CHEBI_38215

http://purl.obolibrary.org/obo/CHEBI_35674

http://purl.obolibrary.org/obo/CHEBI_38070

http://purl.obolibrary.org/obo/CHEBI_35620

label

felodipine

prefixIRI

CHEBI:585948

prefLabel

felodipine

subClassOf

http://purl.obolibrary.org/obo/CHEBI_36683

http://purl.obolibrary.org/obo/CHEBI_50075

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http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29046 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29046 NCIT LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148116 NDFRT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0015772 OCHV LOOM
http://www.co-ode.org/ontologies/galen#Felodipine GALEN LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#4945 OCHV LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/386863007 SNOMEDCT LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000148116 OCVDAE LOOM
http://purl.bioontology.org/ontology/UATC/C08CA02 ATC LOOM
http://purl.obolibrary.org/obo/CHEBI_585948 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_585948 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_585948 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_585948 CCONT SAME_URI
http://purl.obolibrary.org/obo/CHEBI_585948 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_585948 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_585948 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_585948 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_585948 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_585948 DINTO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_585948 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_585948 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_585948 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_585948 CHEBI SAME_URI
http://www.drugbank.ca/drugs/DB01023 FTC LOOM
http://purl.bioontology.org/ontology/NDDF/003602 NDDF LOOM
http://purl.bioontology.org/ontology/VANDF/4020159 VANDF LOOM
http://purl.bioontology.org/ontology/RCD/blc.. RCD LOOM
http://purl.bioontology.org/ontology/RXNORM/4316 RXNORM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.725.203.250 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D015736 RH-MESH LOOM
http://bmi.utah.edu/ontologies/hfontology/C0015772 HFO LOOM
http://purl.jp/bio/4/id/200906048500995334 IOBC LOOM
http://stirdf.jst.go.jp/id/200907041125307092 IOBC LOOM
http://mimi.case.edu/ontologies/2009/9/DrugOntology#felodipine SDO LOOM
http://purl.bioontology.org/ontology/MESH/D015736 MESH LOOM