BioModels Ontology

Last uploaded: April 3, 2012
Preferred Name

digoxin

Definitions

Digitoxin beta-hydroxylated at C-12. A cardiac glycoside extracted from the foxglove plant, Digitalis lanata, it is used to control ventricular rate in atrial fibrillation and in the management of congestive heart failure with atrial fibrillation, but the margin between toxic and therapeutic doses is small.

ID

http://purl.obolibrary.org/obo/CHEBI_4551

alternative term

InChIKey=LTMHDMANZUZIPE-PUGKRICDSA-N

12beta-hydroxydigitoxin

(3beta,5beta,12beta)-3-{[2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl]oxy}-12,14-dihydroxycard-20(22)-enolide

[H][C@]12CC[C@]3([H])[C@]([H])(C[C@@H](O)[C@]4(C)[C@H](CC[C@]34O)C3=CC(=O)OC3)[C@@]1(C)CC[C@@H](C2)O[C@H]1C[C@H](O)[C@H](O[C@H]2C[C@H](O)[C@H](O[C@H]3C[C@H](O)[C@H](O)[C@@H](C)O3)[C@@H](C)O2)[C@@H](C)O1

InChI=1S/C41H64O14/c1-19-36(47)28(42)15-34(50-19)54-38-21(3)52-35(17-30(38)44)55-37-20(2)51-33(16-29(37)43)53-24-8-10-39(4)23(13-24)6-7-26-27(39)14-31(45)40(5)25(9-11-41(26,40)48)22-12-32(46)49-18-22/h12,19-21,23-31,33-38,42-45,47-48H,6-11,13-18H2,1-5H3/t19-,20-,21-,23-,24+,25-,26-,27+,28+,29+,30+,31-,33+,34+,35+,36-,37-,38-,39+,40+,41+/m1/s1

digoxin

definition

Digitoxin beta-hydroxylated at C-12. A cardiac glycoside extracted from the foxglove plant, Digitalis lanata, it is used to control ventricular rate in atrial fibrillation and in the management of congestive heart failure with atrial fibrillation, but the margin between toxic and therapeutic doses is small.

has role

http://purl.obolibrary.org/obo/CHEBI_53000

http://purl.obolibrary.org/obo/CHEBI_38070

label

digoxin

prefixIRI

CHEBI:4551

prefLabel

digoxin

subClassOf

http://purl.obolibrary.org/obo/CHEBI_38092

http://purl.obolibrary.org/obo/CHEBI_60583

Delete Subject Author Type Created
No notes to display
Create New Mapping

Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/CPT/1022259 CPT LOOM
http://purl.obolibrary.org/obo/dinto_2861 DINTO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.808.155.160.349 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D004077 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#3946 OCHV LOOM
http://purl.obolibrary.org/obo/CHEBI_4551 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_4551 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4551 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_4551 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4551 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_4551 DINTO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4551 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_4551 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4551 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_4551 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4551 HINO LOOM
http://purl.obolibrary.org/obo/CHEBI_4551 HINO SAME_URI
http://bmi.utah.edu/ontologies/hfontology/C0012265 HFO LOOM
http://purl.bioontology.org/ontology/CSP/0567-2682 CRISP LOOM
http://purl.bioontology.org/ontology/RXNORM/3407 RXNORM LOOM
http://d-nb.info/gnd/4012306-6 FAST-TOPICAL LOOM
http://purl.bioontology.org/ontology/SNMI/C-80330 SNMI LOOM
http://purl.bioontology.org/ontology/VANDF/4018047 VANDF LOOM
http://purl.bioontology.org/ontology/UATC/C01AA05 ATC LOOM
http://purl.obolibrary.org/obo/XCO_0000619 XCO LOOM
http://purl.obolibrary.org/obo/XCO_0000619 XCO LOOM
http://purl.bioontology.org/ontology/NDDF/000593 NDDF LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000485249 PDQ LOOM
http://purl.bioontology.org/ontology/LNC/LP14714-7 LOINC LOOM
https://bioportal.bioontology.org/ontologies/DMTO.owl#DMTO_0001804 DMTO LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Digoxin APAONTO LOOM
http://purl.bioontology.org/ontology/MESH/D004077 MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.808.155.580.130.500.436 RH-MESH LOOM
http://stirdf.jst.go.jp/id/200907085872788919 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D09.408.180.261.436 RH-MESH LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28990 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28990 NCIT LOOM
https://bioportal.bioontology.org/ontologies/FTDM.owl#DMTO_0001804 FASTO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146388 NDFRT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0337449 OCHV LOOM
http://purl.jp/bio/4/id/200906050095521421 IOBC LOOM
http://www.drugbank.ca/drugs/DB00390 FTC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU001808 LOINC LOOM
http://www.co-ode.org/ontologies/galen#Digoxin GALEN LOOM
http://id.loc.gov/authorities/subjects/sh85037995 FAST-TOPICAL LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387461009 SNOMEDCT LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000146388 OCVDAE LOOM