BioModels Ontology

Last uploaded: April 3, 2012
Preferred Name

cyproheptadine

Synonyms
Definitions

The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.

ID

http://purl.obolibrary.org/obo/CHEBI_4046

alternative term

cyproheptadinum

4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-methylpiperidine

1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)piperidine

ciproheptadina

5-(1-methylpiperidylidene-4)-5H-dibenzo(a,d)cyclopheptene

C21H21N

InChIKey=JJCFRYNCJDLXIK-UHFFFAOYSA-N

cyproheptadine

4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine

1-methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine

4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine

4-(5-dibenzo(a,d)cyclohepten-5-ylidine)-1-methylpiperidine

Cyproheptadine

4-Dibenzo[a,d]cyclohepten-5-ylidene-1-methyl-piperidine

CYPROHEPTADINE

CN1CCC(CC1)=C1c2ccccc2C=Cc2ccccc12

InChI=1S/C21H21N/c1-22-14-12-18(13-15-22)21-19-8-4-2-6-16(19)10-11-17-7-3-5-9-20(17)21/h2-11H,12-15H2,1H3

definition

The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.

has role

http://purl.obolibrary.org/obo/CHEBI_37955

http://purl.obolibrary.org/obo/CHEBI_55324

http://purl.obolibrary.org/obo/CHEBI_48279

http://purl.obolibrary.org/obo/CHEBI_59683

http://purl.obolibrary.org/obo/CHEBI_50857

label

cyproheptadine

prefixIRI

CHEBI:4046

prefLabel

cyproheptadine

subClassOf

http://purl.obolibrary.org/obo/CHEBI_32876

http://purl.obolibrary.org/obo/CHEBI_26151

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http://purl.obolibrary.org/obo/CHEBI_4046 PDRO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4046 FIDEO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4046 DINTO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4046 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4046 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4046 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4046 UPHENO SAME_URI
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D003533 RH-MESH LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016901 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147793 NDFRT LOOM
http://purl.jp/bio/4/id/200906004993207987 IOBC LOOM
http://purl.bioontology.org/ontology/RCD/x01Dw RCD LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.615.181.384.340 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNMI/C-51030 SNMI LOOM
http://purl.obolibrary.org/obo/NCIT_C61695 BERO LOOM
http://purl.bioontology.org/ontology/ATC/R06AX02 ATC LOOM
http://purl.bioontology.org/ontology/NDDF/004617 NDDF LOOM
http://purl.obolibrary.org/obo/OMIT_0004819 OMIT LOOM
http://purl.bioontology.org/ontology/CSP/0780-7203 CRISP LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#3537 OCHV LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61695 NCIT LOOM
http://purl.bioontology.org/ontology/MESH/D003533 MESH LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147793 ODAE LOOM
http://purl.bioontology.org/ontology/RXNORM/3013 RXNORM LOOM
http://purl.bioontology.org/ontology/LNC/LP18932-1 LOINC LOOM
http://purl.obolibrary.org/obo/CHEBI_4046 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_4046 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_4046 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_4046 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_4046 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_4046 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_4046 UPHENO LOOM
http://purl.obolibrary.org/obo/MESH_D003533 BERO LOOM
https://go.drugbank.com/drugs/DB00434 MDM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.621.160 RH-MESH LOOM
http://stirdf.jst.go.jp/id/200907069431147637 IOBC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0010620 OCHV LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.559.847.181.384.340 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/MTHU006211 LOINC LOOM
http://www.drugbank.ca/drugs/DB00434 FTC LOOM
http://purl.bioontology.org/ontology/VANDF/4019701 VANDF LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372683000 SNOMEDCT LOOM