BioModels Ontology

Last uploaded: April 3, 2012
Preferred Name

butenafine

Synonyms
Definitions

Trimethylamine in which hydrogen atoms attached to different methyl groups are substituted by 1-naphthyl and 4-tert-butylphenyl groups. It is an inhibitor of squalene epoxidase, an enzyme responsible for the creation of sterols needed in fungal cell membranes, and is used as its hydrochloride salt for treatment of dermatological fungal infections.

ID

http://purl.obolibrary.org/obo/CHEBI_3238

alternative term

4-tert-butylbenzyl(methyl)(1-naphthalenemethyl)amine

InChIKey=ABJKWBDEJIDSJZ-UHFFFAOYSA-N

(4-tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanamine

butenafine

N-(p-tert-butylbenzyl)-N-methyl-1-naphthalenemethylamine

1-(4-tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanamine

butenafinum

Butenafine

CN(Cc1ccc(cc1)C(C)(C)C)Cc1cccc2ccccc12

(4-tert-Butyl-benzyl)-methyl-naphthalen-1-ylmethyl-amine

C23H27N

InChI=1S/C23H27N/c1-23(2,3)21-14-12-18(13-15-21)16-24(4)17-20-10-7-9-19-8-5-6-11-22(19)20/h5-15H,16-17H2,1-4H3

butenafina

definition

Trimethylamine in which hydrogen atoms attached to different methyl groups are substituted by 1-naphthyl and 4-tert-butylphenyl groups. It is an inhibitor of squalene epoxidase, an enzyme responsible for the creation of sterols needed in fungal cell membranes, and is used as its hydrochloride salt for treatment of dermatological fungal infections.

has role

http://purl.obolibrary.org/obo/CHEBI_59285

http://purl.obolibrary.org/obo/CHEBI_35718

label

butenafine

prefixIRI

CHEBI:3238

prefLabel

butenafine

subClassOf

http://purl.obolibrary.org/obo/CHEBI_32876

http://purl.obolibrary.org/obo/CHEBI_25477

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http://purl.obolibrary.org/obo/CHEBI_3238 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3238 PDRO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3238 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3238 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3238 CHEBI LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000022059 NDFRT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C72959 NCIT LOOM
http://purl.obolibrary.org/obo/dinto_DB01091 DINTO LOOM
http://purl.bioontology.org/ontology/VANDF/4024054 VANDF LOOM
http://purl.jp/bio/4/id/200906095176800248 IOBC LOOM
http://purl.bioontology.org/ontology/MESH/C067594 MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#16175 OCHV LOOM
http://purl.obolibrary.org/obo/NCIT_C72959 BERO LOOM
http://stirdf.jst.go.jp/id/200907088578946092 IOBC LOOM
http://www.drugbank.ca/drugs/DB01091 FTC LOOM
http://purl.bioontology.org/ontology/NDDF/006293 NDDF LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/373449007 SNOMEDCT LOOM
https://go.drugbank.com/drugs/DB01091 MDM LOOM
http://purl.obolibrary.org/obo/CHEBI_3238 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_3238 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_3238 DRON LOOM
http://www.phoc.org.cn/pmo/class/PMO_00025790 PMAPP-PMO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0107497 OCHV LOOM
http://purl.bioontology.org/ontology/RXNORM/47461 RXNORM LOOM
http://purl.bioontology.org/ontology/ATC/D01AE23 ATC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C067594 RH-MESH LOOM