Antibiotic Resistance Ontology

Last uploaded: March 20, 2024
Preferred Name

carbapenem

Synonyms
Definitions

Carbapenems are a class of beta-lactam antibiotics with a broad spectrum of antibacterial activity, and have a structure which renders them highly resistant to beta-lactamases. Carbapenem antibiotics are bactericidal, and act by inhibiting the synthesis of the peptidoglycan layer of bacterial cell walls. The peptidoglycan layer is important for cell wall structural integrity, especially in Gram-positive organisms.

ID

http://purl.obolibrary.org/obo/ARO_0000020

definition

Carbapenems are a class of beta-lactam antibiotics with a broad spectrum of antibacterial activity, and have a structure which renders them highly resistant to beta-lactamases. Carbapenem antibiotics are bactericidal, and act by inhibiting the synthesis of the peptidoglycan layer of bacterial cell walls. The peptidoglycan layer is important for cell wall structural integrity, especially in Gram-positive organisms.

has_obo_namespace

antibiotic_resistance

id

ARO:0000020

label

carbapenem

notation

ARO:0000020

prefLabel

carbapenem

subClassOf

http://purl.obolibrary.org/obo/ARO_3000007

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