loading...| Preferred Name |
methicillin |
|
| Synonyms |
meticillin Meticillinum Staphcillin Metacillin Methicillinum Dimocillin Meticilina Methycillin Meticilline |
|
| Definitions |
Derived from penicillin to combat penicillin-resistance, methicillin is insensitive to beta-lactamases (also known as penicillinases) secreted by many penicillin-resistant bacteria. Methicillin is bactericidal, and acts by inhibiting the synthesis of the peptidoglycan layer of bacterial cell walls. The peptidoglycan layer is important for cell wall structural integrity, especially in Gram-positive organisms. |
|
| ID |
http://purl.obolibrary.org/obo/ARO_0000015 |
|
| database_cross_reference |
pubchem.compound:6087 |
|
| definition |
Derived from penicillin to combat penicillin-resistance, methicillin is insensitive to beta-lactamases (also known as penicillinases) secreted by many penicillin-resistant bacteria. Methicillin is bactericidal, and acts by inhibiting the synthesis of the peptidoglycan layer of bacterial cell walls. The peptidoglycan layer is important for cell wall structural integrity, especially in Gram-positive organisms. |
|
| has_exact_synonym |
meticillin Meticillinum Staphcillin Metacillin Methicillinum Dimocillin Meticilina Methycillin Meticilline |
|
| has_obo_namespace |
antibiotic_resistance |
|
| id |
ARO:0000015 |
|
| label |
methicillin |
|
| notation |
ARO:0000015 |
|
| prefLabel |
methicillin |
|
| subClassOf |