Tumor Necrosis Factor Ligand Superfamily Member 6

Apoptosis Antigen Ligand 1

CD178 Antigen

CD95 Ligand

FAS-Ligand

FASL

Fas Ligand

Fas-L

TNFSF6

Tumor Necrosis Factor Ligand Superfamily Member 6

FAS_Ligand

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#FAS_Ligand

C20529

NCIFAS ligand is a TNF family, type II transmembrane protein expressed on many cell types and secreted from T-cells upon TCR ligation by MHC/peptide complexes residing on antigen presenting cells. FAS ligand triggers cell death by binding to the cell surface receptor FAS, another transmembrane protein member of the TNF receptor family. FAS ligand is expressed in activated splenocytes and thymocytes, consistent with its involvement in T-cell-mediated cytotoxicity, and in the liver, lung, ovary, and heart, where its function is unclear. (from OMIM 134638 and NCI)

Apoptosis Antigen Ligand 1SYNCI

Tumor Necrosis Factor Ligand Superfamily Member 6PTNCI

FAS-LigandSYNCI

FASLSYNCI

Fas-LSYNCI

Fas LigandSYNCI

CD95 LigandSYNCI

TNFSF6SYNCI

CD178 AntigenSYNCI

356

CL100442

134638

'Tumor Necrosis Factor Family Protein' and (Gene_Product_Expressed_In_Tissue some Thymocyte) and (Gene_Product_Has_Biochemical_Function some 'Apoptosis Promoter') and (Gene_Product_Has_Biochemical_Function some Cytokine) and (Gene_Product_Encoded_By_Gene some 'FASLG Gene') and (Gene_Product_Plays_Role_In_Biological_Process some Apoptosis) and (Gene_Product_Plays_Role_In_Biological_Process some 'Intercellular Communication') and (Gene_Product_Is_Element_In_Pathway some 'CTL-mediated Immune Response Pathway') and (Gene_Product_Is_Element_In_Pathway some 'Fas Signaling Pathway') and (Gene_Product_Is_Element_In_Pathway some 'HIV-I Nef in Apoptosis Pathway') and (Gene_Product_Is_Element_In_Pathway some 'HSP27 Regulation Pathway') and (Gene_Product_Is_Element_In_Pathway some 'IL2RB Pathway') and (Gene_Product_Is_Element_In_Pathway some 'Keratinocyte Differentiation Pathway') and (Gene_Product_Is_Element_In_Pathway some 'Cell Cycle Progression Pathway') and (Gene_Product_Is_Element_In_Pathway some 'PTEN-Dependent Cell Cycle Arrest and Apoptosis Pathway') and (Gene_Product_Is_Element_In_Pathway some 'HIV Induced T Cell Apoptosis Pathway') and (Gene_Product_Is_Element_In_Pathway some 'Apoptosis Pathway') and (Gene_Product_Is_Element_In_Pathway some 'Regulation of Apoptosis Pathway') and (Gene_Product_Is_Element_In_Pathway some 'AKT Signaling Pathway') and (Gene_Product_Is_Element_In_Pathway some 'Antigen Dependent B Cell Activation Pathway') and (Gene_Product_Is_Element_In_Pathway some 'Bystander B Cell Activation Pathway') and (Gene_Product_Has_Associated_Anatomy some 'Plasma Membrane') and (Gene_Product_Has_Structural_Domain_Or_Motif some 'Transmembrane Domain')

Tumor Necrosis Factor Ligand Superfamily Member 6

Tumor Necrosis Factor Ligand Superfamily Member 6

Amino Acid, Peptide, or Protein

P48023

CD178 Antigen

TNFSF6

Fas Ligand

Tumor Necrosis Factor Ligand Superfamily Member 6

Apoptosis Antigen Ligand 1

Fas-L

CD95 Ligand

FASL

FAS-Ligand