NCI Thesaurus - Chemokine (C-C Motif) Receptor 6 - Terms | NCBO BioPortal

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Preferred Name (Preferred_Name)	Chemokine (C-C Motif) Receptor 6
Synonyms (Synonym)	BN-1 C-C CKR-6 C-C Chemokine Receptor Type 6 CC-CKR-6 CCR-6 CCR6 CCR6 Protein CKR-L3 CKR6 CKRL3 CMKBR6 Chemokine (C-C Motif) Receptor 6 Chemokine (C-C) Receptor 6 Chemokine Receptor-Like 3 DCR2 DRY-6 DRY6 G Protein-Coupled Receptor 29 GPR-CY4 GPR29 GPRCY4 LARC Receptor STRL22 Seven-Transmembrane Receptor, Lymphocyte, 22
ID	C-C_Motif_Chemokine_Receptor-6
Full Id	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C-C_Motif_Chemokine_Receptor-6
Code	C25778
Definition	NCIChemokine (C-C Motif) Receptor 6, encoded by the CCR6 gene, is a member of the beta chemokine receptor family and a seven transmembrane protein similar to G protein-coupled receptor. The CCR6 gene is preferentially expressed by immature dendritic cells and memory T cells. This receptor mediates intracellular calcium flux and binds specifically to the CC chemokine macrophage inflammatory protein 3 alpha (MIP-3 alpha). It is important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. (From LocusLink and NCI)
Full Syn	Chemokine Receptor-Like 3SYNCI DRY-6SYNCI Chemokine (C-C) Receptor 6SYNCI Chemokine (C-C Motif) Receptor 6PTNCI BN-1SYNCI GPR-CY4SYNCI DCR2SYNCI CKRL3SYNCI STRL22SYNCI DRY6SYNCI CKR-L3SYNCI LARC ReceptorSYNCI C-C Chemokine Receptor Type 6SYNCI Seven-Transmembrane Receptor, Lymphocyte, 22SYNCI G Protein-Coupled Receptor 29SYNCI GPR29SYNCI CC-CKR-6SYNCI C-C CKR-6SYNCI CCR6 ProteinSYNCI CCR6SYNCI CMKBR6SYNCI GPRCY4SYNCI CCR-6SYNCI CKR6SYNCI
Nci Meta Cui	CL101522
Equivalent Class	'Chemokine Receptor' and (Gene_Product_Has_Organism_Source some Human) and (Gene_Product_Expressed_In_Tissue some 'Dendritic Cell') and (Gene_Product_Expressed_In_Tissue some T-Lymphocyte) and (Gene_Product_Has_Biochemical_Function some 'Chemokine Receptor') and (Gene_Product_Encoded_By_Gene some 'CCR6 Gene') and (Gene_Product_Plays_Role_In_Biological_Process some 'Inflammatory Response') and (Gene_Product_Plays_Role_In_Biological_Process some 'Cell Lineage') and (Gene_Product_Plays_Role_In_Biological_Process some 'Immune Response') and (Gene_Product_Plays_Role_In_Biological_Process some 'Calcium Signaling') and (Gene_Product_Plays_Role_In_Biological_Process some 'Cell Differentiation')
Preferred Name	Chemokine (C-C Motif) Receptor 6
Label	Chemokine (C-C Motif) Receptor 6
Semantic Type	Amino Acid, Peptide, or Protein
Swiss Prot	P51684
Synonym	C-C Chemokine Receptor Type 6 Seven-Transmembrane Receptor, Lymphocyte, 22 GPRCY4 CKR-L3 GPR29 Chemokine (C-C Motif) Receptor 6 DCR2 CKR6 CCR-6 STRL22 GPR-CY4 BN-1 Chemokine (C-C) Receptor 6 DRY-6 Chemokine Receptor-Like 3 CC-CKR-6 LARC Receptor CMKBR6 CCR6 C-C CKR-6 CKRL3 CCR6 Protein G Protein-Coupled Receptor 29 DRY6

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Mapping To	Source	Comment	Relationship Type	Mapped By	Mapped On	Notes
CHEMOKINE, CC MOTIF, RECEPTOR 6 (Online Mendelian Inheritance in Man)	LOOM		skos:closeMatch	amirg	05/17/10	View Notes

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