NCI Thesaurus - Arbutamine - Terms | NCBO BioPortal

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Preferred Name (Preferred_Name)	Arbutamine
Synonyms (Synonym)	ARBUTAMINE Arbutamine
ID	Arbutamine
Full Id	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Arbutamine
Cas Registry	128470-16-6
Code	C65238
Concept In Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Contributing Source	FDA
Definition	NCIA synthetic catecholamine with positive chronotropic and inotropic properties, used in echocardiography and diagnostic coronary angiography. Arbutamine binds to and activates beta-1 adrenergic receptors in the myocardium, thereby increasing heart rate and increasing force of myocardial contraction. By exerting a chronotropic and inotropic effect, arbutamine mimics the cardiac stress caused by exercise that may prevent adequate tissue perfusion and oxygenation, and may provoke myocardial ischemia in patients with coronary artery disease.
Fda Unii Code	B07L15YAEV
Full Syn	ArbutaminePTNCI ARBUTAMINEPTFDAB07L15YAEV
Has Salt Form	Arbutamine Hydrochloride
Preferred Name	Arbutamine
Label	Arbutamine
Semantic Type	Pharmacologic Substance
Synonym	Arbutamine ARBUTAMINE
Sub Class Of	Beta-Adrenergic Agonist

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Mapping To	Source	Comment	Relationship Type	Mapped By	Mapped On	Notes
arbutamine (Medical Subject Headings)	LOOM		skos:closeMatch	amirg	05/17/10	View Notes
arbutamine (Chemical entities of biological interest)	LOOM		skos:closeMatch	amirg	05/17/10	View Notes
ARBUTAMINE (National Drug File)	LOOM		skos:closeMatch	amirg	05/17/10	View Notes

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